1911 – Six Franciscans arrive in North America (Pineville, Louisiana)
1913 – St. Francis Hospital and Nursing School opens in Monroe, Louisiana
1923 – Our Lady of the Lake Hospital and Nursing School opens in Baton Rouge, Louisiana
1949 – Our Lady of Lourdes Hospital opens in Lafayette, Louisiana
1984 – Franciscan Missionaries of Our Lady Health System is established
1990 – Our Lady of the Lake School of Nursing becomes Our Lady of the Lake College in Baton Rouge, Louisiana
1996 – Assumption Community Hospital becomes part of the health system in Napoleonville, Louisiana
2000 – St. Elizabeth Hospital becomes part of the health system in Gonzales, Louisiana
2005 – St. Francis North Monroe is acquired by St. Francis Medical Center
2009 – Senior Service Division is created in Baton Rouge, Louisiana
2011 – Franciscan Health & Wellness program is created in Louisiana and in other states
2013 – Our Lady of the Lake Livingston opens in Livingston, Louisiana
2014 – Our Lady of the Angels Hospital opens in Bogalusa, Louisiana
2016 – Our Lady of the Lake College becomes Franciscan Missionaries of Our Lady University
2019 – Our Lady of the Lake Children’s Hospital opens its own campus in Baton Rouge, Louisiana
2019 – St. Elizabeth Hospital becomes Our Lady of the Lake Ascension
2019 – Women's & Children's Hospital is acquired and joins the Our Lady of Lourdes family in Lafayette, Louisiana
2019 – St. Dominic Health Services in Jackson, Mississippi joins the health system with the transfer of sponsorship from the Dominican Sisters of Springfield, Ill.
